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8064

Question 8064 — diseases

openFrance· National Assembly· FR

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1 July 2025

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1 July 2025

Summary

Mr. Mathieu Lefèvre draws the attention of the Minister to the Minister of Labor, Health, Solidarity and Families, responsible for health and access to care, to the situation of patients who have developed meningiomas following prolonged consumption of synthetic progestins such as Androcur, Lutéran or Lutényl, prescribed as part of medical treatments. From the beginning of the 2000s, warning signs on the dangerousness of these pharmaceutical specialties were already available. However, it is only since 2018 that the National Medicines Safety Agency (ANSM) has taken measures to alert health professionals and patients of the consequences incurred. Several scientific studies now establish a causal link between prolonged exposure to these drugs and the development of brain tumors. cancerous (meningiomas), sometimes multiple and causing serious after-effects. To date, more than 750 files have been compiled or are in the process of being compiled, 70 legal or amicable proceedings have been initiated and around forty definitive expert reports confirm this causal link. The AMAVEA association has repeatedly called on the Ministry of Health to propose the establishment of a compensation system amicable, like what was done for Médiator or Dépakine. Accompanied by a panel of experts specializing in synthetic progestins, this system would make it possible to harmonize procedures, avoid particularly grueling medical assessments for victims and ensure faster and more equitable compensation. It could, moreover, be integrated into the next social security financing bill (PLFSS) for 2025. Also, he asks it to specify the measures that the Government intends to take with a view to setting up such an amicable compensation system and, more broadly, the actions envisaged to help people affected by the serious side effects of these treatments.

Machine translation from French. The official text remains authoritative.

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